Research
NMN Fact Sheet
| Molecular formula: |
C11H15N2O8P |
| Molecular weight: |
334.22 g/mol |
| Purity: |
99%+ |
| Synonyms |
- 1094-61-7
- beta-Nicotinamide mononucleotide
- nicotinamide mononucleotide
- NMN zwitterion
- beta-NMN
|
| Research Applications: |
- Metabolic Health
- Anti-Aging and Longevity
- Cognitive Function
- Chronic Conditions
|
NMN (Nicotinamide Mononucleotide) Research
Nicotinamide Mononucleotide (NMN) is a molecule that has been extensively studied for its potential health benefits across various domains. In the realm of metabolic health, NMN has shown promise in protecting against diabetes and other metabolic disorders by boosting NAD+ levels, a vital molecule involved in several metabolic reactions.
NMN has been studied as a potential anti-aging supplement. It has been found to mitigate physiological decline and has been associated with beneficial effects in in vivo studies. When used as a dietary supplement, NMN powder can potentially prevent or alleviate a wide range of diseases such as age-related disorders.
NMN and Metabolic Health
Research suggests that NMN can contribute to metabolic health by boosting NAD+ levels, a vital molecule involved in several metabolic reactions. This increase in NAD+ levels has been shown to mitigate physiological decline and protect against diseases such as diabetes and diabetic neuropathy.
NMN Supports Energy Metabolism
Nicotinamide Mononucleotide (NMN) plays a beneficial role in energy metabolism by acting as a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme central to cellular energy production. NAD+ is involved in various cellular processes, including metabolic pathways, DNA repair, and immune cell activity. However, NAD+ levels decrease with age, leading to a decline in these vital processes and contributing to age-related disorders.
NMN Supports Healthy Aging
NMN and other NAD+ derivatives are thought to be closely related to healthy aging. They can potentially have a prophylactic and therapeutic impact on functional decline, improving age-associated conditions such as neurodegenerative disorders, cardiomyopathy, obesity, and diabetes.
NMN and Longevity
NMN has been shown to promote longevity by restoring NAD+ levels, thereby delaying or even reversing several age-related disorders. It has demonstrated therapeutic potential in age-related chronic conditions such as diabetes, cardiovascular issues, and cognitive impairment. NMN also mitigates age-associated physiological changes in various organs, including the liver, adipose tissue, muscle, pancreas, kidney, retina, and central nervous system.
NMN Improves Cognitive Function
Cognitive function benefits have also been associated with NMN supplementation. A study on aged mice showed that NMN supplementation rescued neurovascular coupling responses and improved spatial working memory and gait coordination. This suggests that restoring NAD+ concentration may exert beneficial effects on cognitive responses in aging.
NMN Helps Manage Chronic Conditions
NMN also shows promise in managing chronic conditions. For instance, it is being studied as a potential treatment for chronic insomnia, with the hypothesis that NMN supplementation could improve sleep quality. Additionally, NMN has been found to inhibit α-amylase and α-glucosidase enzymes, which could lead to a decrease in glucose absorption, offering a potential management strategy for diabetes mellitus.
FAQ
What is NMN (Nicotinamide Mononucleotide)?
Imagine a molecule that could be the key to unlocking the fountain of youth, promoting energy metabolism and cellular health, and supporting healthy aging and longevity. That molecule is Nicotinamide Mononucleotide (NMN), a naturally occurring compound found in every living cell.
NMN is a precursor to the essential coenzyme NAD+, which plays a vital role in various biological processes, including energy production, DNA repair, and cellular stress responses. As we age, our NAD+ levels decline, leading to a decrease in cellular function and overall vitality. By supplementing with NMN, we can boost our NAD+ levels, rejuvenating our cells and promoting a symphony of interlocking transformations that support a wide array of physiological functions.
What are the Benefits of an NMN Supplement?
Some of the numerous potential benefits of taking NMN supplements include:
- Increased NAD+ biosynthesis, which is essential for various cellular processes
- Suppression of age-related adipose tissue inflammation
- Enhanced insulin secretion and insulin action, potentially benefiting diabetic or obese individuals
- Improved mitochondrial function, supporting energy metabolism
- Improved neuronal function in the brain, potentially slowing cognitive decline
- Protection against ischemia and/or reperfusion injury in the heart
- Restoration of skeletal muscle in aged mice
- Improved insulin sensitivity and heart function
- Reduced tiredness
- Support for cardiovascular health
- Maintenance of cognitive function and muscle function
- Anti-inflammatory effects
It is important to note that research on NMN supplements is still emerging, and more studies are needed to confirm these benefits in humans.
How Bioavailable is NMN Powder Supplement?
Studies have shown that NMN is quickly absorbed from the gut into blood circulation within 2-3 minutes and cleared from blood circulation into tissues within 15 minutes. This rapid absorption and conversion to NAD+ suggest that NMN has high bioavailability. In one study, NMN supplementation for 12 weeks in healthy volunteers showed no abnormalities in physiological and laboratory tests, and no obvious adverse effects were observed. NAD+ levels in whole blood were significantly increased after NMN administration, indicating that NMN is effectively absorbed and utilized in the body.
Our high purity and potency pure NMN powder supplement is an ideal form of Nicotinamide Mononucleotide for maximum absorption and bioavailability.
Is NMN the Same as Nicotinamide Adenine Dinucleotide?
NMN (Nicotinamide Mononucleotide) is not the same as NAD (Nicotinamide Adenine Dinucleotide). They are distinct molecules with different roles in the body. NMN is a precursor to NAD+, meaning it chemically transforms into NAD+ in your cells. It is absorbed into your bloodstream and converts into NAD+, which is then stored in your muscles and vital organs, helping them function in peak condition.
Can Your NMN Dietary Supplement Be Used As Sublingual Powder?
Yes, NMN (Nicotinamide Mononucleotide) powder can be used sublingually. This method of administration allows the NMN to be absorbed directly into the bloodstream through the soft tissue in the mouth, bypassing the digestive system.
Can NMN Be Combined with Resveratrol?
Yes, NMN (Nicotinamide Mononucleotide) can be combined with Resveratrol. Research has even shown that these two compounds can work synergistically to boost NAD+ levels.
Does NMN Work for DNA Repair?
Research has shown that supplementation with NMN can increase NAD+ biosynthesis, which in turn enhances the capacity for DNA repair. For instance, a study found that NMN supplementation decreased the accumulation of endogenous DNA damage and improved DNA repair capacity in cells.
Does NMN Work for Anti-Aging?
In animal studies, NMN has demonstrated a wide array of beneficial effects, including suppressing age-associated weight gain, enhancing energy metabolism, improving insulin sensitivity, and improving eye function. It has also shown promise in protecting against skin aging caused by environmental factors and reversing blood vessel aging in middle-aged adults with high weight and blood glucose levels.
Some clinical trials have also shown improvements in sleep quality, muscle function, and skin health in middle-aged and older adults but long-term studies are still required to fully understand the true potential of NMN as an anti-aging supplement.
Where to Buy NMN Powder?
Limitless Life Nootropics offers Nicotinamide Mononucleotide in a convenient powder supplement for easy supplementation and maximum absorption. We also offer a wide range of peptides to buy online strictly for research purposes.
