Research
NMN Fact Sheet
| Molecular formula: |
C11H15N2O8P |
| Molecular weight: |
334.22Â g/mol |
| Purity: |
99%+ |
| Synonyms |
- 1094-61-7
- beta-Nicotinamide mononucleotide
- nicotinamide mononucleotide
- NMN zwitterion
- beta-NMN
|
| Research Applications: |
- Metabolic Health
- Anti-Aging and Longevity
- Cognitive Function
- Chronic Conditions
|
NMN (Nicotinamide Mononucleotide) Research
Nicotinamide Mononucleotide (NMN) is a molecule that has been extensively studied for its potential health benefits across various domains. Concerning metabolic health, NMN has shown promise in protecting against diabetes and other metabolic disorders by boosting NAD+ levels, a vital molecule involved in several metabolic reactions.
NMN and Metabolic Health
Research suggests that NMN can contribute to metabolic health by boosting NAD+ levels, a vital molecule involved in several metabolic reactions. This increase in NAD+ levels has been shown to mitigate physiological decline and protect against diseases such as diabetes and diabetic neuropathy [R].
NMN Supports Energy Metabolism
Nicotinamide Mononucleotide (NMN) plays a beneficial role in energy metabolism by acting as a precursor to Nicotinamide Adenine Dinucleotide (NAD+), a coenzyme central to cellular energy production. NAD+ is involved in various cellular processes, including metabolic pathways, DNA repair, and immune cell activity. However, NAD+ levels decrease with age, leading to a decline in these vital processes and contributing to age-related disorders.
NMN Supports Healthy Aging
NMN and other NAD+ derivatives are thought to be closely related to healthy aging. They can potentially have a prophylactic and therapeutic impact on functional decline, improving age-associated conditions such as neurodegenerative disorders, cardiomyopathy, obesity, and diabetes [R].
NMN and Longevity
NMN has been shown to promote longevity by restoring NAD+ levels, thereby delaying or even reversing several age-related disorders. It has demonstrated therapeutic potential in age-related chronic conditions such as diabetes, cardiovascular issues, and cognitive impairment. NMN also mitigates age-associated physiological changes in various organs, including the liver, adipose tissue, muscle, pancreas, kidney, retina, and central nervous system [R].
NMN Improves Cognitive Function
Cognitive function benefits have also been associated with NMN supplementation. A study on aged mice showed that NMN supplementation rescued neurovascular coupling responses and improved spatial working memory and gait coordination. This suggests that restoring NAD+ concentration may exert beneficial effects on cognitive responses in aging [R].
NMN Helps Manage Chronic Conditions
NMN also shows promise in managing chronic conditions. For instance, it is being studied as a potential treatment for chronic insomnia, with the hypothesis that NMN supplementation could improve sleep quality. Additionally, NMN has been found to inhibit α-amylase and α-glucosidase enzymes, which could lead to a decrease in glucose absorption, offering a potential management strategy for diabetes mellitus [R][R].
FAQ
What is NMN (Nicotinamide Mononucleotide)?
Nicotinamide Mononucleotide (NMN) is a precursor for NAD+ biosynthesis, a critical coenzyme found in every cell of our bodies. NMN supplementation has been shown in various in vitro and in vivo studies to increase NAD+ concentration, which could potentially mitigate aging-related disorders such as oxidative stress, DNA damage, neurodegeneration, and inflammatory responses. It has been the subject of numerous studies, with some suggesting that NMN supplementation can increase NAD+ biosynthesis, potentially impacting age-related conditions [R].
What are the Benefits of NMN?
Nicotinamide mononucleotide (NMN) is a molecule that has been extensively studied for its potential benefits in the context of aging and various diseases. Here are some of the key benefits observed in research studies:
- Increased NAD+ biosynthesis, which is essential for various cellular processes
- Suppression of age-related adipose tissue inflammation
- Enhanced insulin secretion and insulin action, potentially benefiting diabetic or obese individuals
- Improved mitochondrial function, supporting energy metabolism
- Improved neuronal function in the brain, potentially slowing cognitive decline
- Protection against ischemia and/or reperfusion injury in the heart
- Restoration of skeletal muscle in aged mice
- Improved insulin sensitivity and heart function
- Reduced tiredness
- Support for cardiovascular health
- Maintenance of cognitive function and muscle function
- Anti-inflammatory effects
It is important to note that research on NMN supplements is still emerging, and more studies are needed to confirm these benefits.
Is NMN the Same as Nicotinamide Adenine Dinucleotide?
NMN (Nicotinamide Mononucleotide) is not the same as NAD (Nicotinamide Adenine Dinucleotide). They are distinct molecules with different roles in the body. NMN is a precursor to NAD+, meaning it chemically transforms into NAD+ in cells.
Has NMN Been Studied in Combination with Resveratrol?
NMN (nicotinamide mononucleotide) has indeed been studied in combination with resveratrol. Research conducted by a China-based team has shown that when NMN is administered orally with resveratrol to adult mice, the two substances work synergistically to increase NAD+ levels in the heart by 1.59-fold and 1.72-fold, respectively, six hours after treatment [R].
Has NMN Been Studied for DNA Repair?
Research has shown that supplementation with NMN can increase NAD+ biosynthesis, which in turn enhances the capacity for DNA repair. For instance, a study found that NMN supplementation decreased the accumulation of endogenous DNA damage and improved DNA repair capacity in cells [R].
Has NMN Been Studied for Anti-Aging?
In animal studies, NMN has demonstrated a wide array of beneficial effects, including suppressing age-associated weight gain, enhancing energy metabolism, improving insulin sensitivity, and improving eye function. It has also shown promise in protecting against skin aging caused by environmental factors and reversing blood vessel aging in middle-aged adults with high weight and blood glucose levels [R].
Some clinical trials have also shown improvements in sleep quality, muscle function, and skin health in middle-aged and older adults but long-term studies are still required to fully understand the true potential of NMN for anti-aging research [R].
Where to Buy NMN Powder?
NMN powder can be purchased online from reputable biotech suppliers such as Limitless Life. Limitless Life offers a wide selection of research-grade USA peptides for sale online for scientific research and development purposes.
Our extensive range of products undergoes rigorous third-party testing to verify the sequential signatures of all research peptides for sale. With our commitment to quality, most orders are promptly sent out on the same day they are placed, accompanied by our unwavering dedication to providing exceptional customer service.
