Coluracetam 99.98%

Rated 5.00 out of 5 based on 1 customer rating
(1 customer review)

$19.99$79.99

This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to out terms and conditions prior to purchase.

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Description

Coluracetam (INN) (code name BCI-540; formerly MKC-231) is a nootropic agent of the racetam family.[1] It was initially developed and tested by the Mitsubishi Tanabe Pharma Corporation for Alzheimer’s disease. After the drug failed to reach endpoints in its clinical trials it was in-licensed by BrainCells Inc for investigations into major depressive disorder (MDD), which was preceded by being awarded a “Qualifying Therapeutic Discovery Program Grant” by the state of California.[2] Findings from phase IIa clinical trials have suggested that it would be a potential medication for comorbid MDD with generalized anxiety disorder (GAD).[3] BrainCells Inc is currently[when?] out-licensing the drug for this purpose.[4][full citation needed] It may also have potential use in prevention and treatment of ischemic retinopathy and retinal and optic nerve injury.[medical citation needed]

Coluracetam has been shown to reverse the loss of choline acetyltransferase production in the medial septal nucleus of rats exposed to phencyclidine (PCP), and is considered a potential therapeutic drug for schizophrenia.[5]
Mechanism of action

Coluracetam enhances high-affinity choline uptake (HACU),[6] which is the rate-limiting step of acetylcholine (ACh) synthesis. Studies have shown coluracetam to improve learning impairment on a single oral dose given to rats which have been exposed to cholinergic neurotoxins. Subsequent studies have shown that it may induce long-lasting procognitive effects in cholinergic neurotoxin-treated rats by changing the choline transporter regulation system.[7]
These statements have not been evaluated by the fda and are not intented to diagnose, treat, cure or prevent any disease

Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, a pure substance, sold as a raw material. We attest to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.

Contents: Coluracetam, Verified by LC/MS to 99.98%% purity.

Legal Disclaimer: This product is not sold as a dietary supplement, but instead as a pure chemical substance for research purposes.

1 review for Coluracetam 99.98%

  1. Rated 5 out of 5

    (verified owner)

    Potent pharma delivered in high quality lab tested powder form in sterile bottle; excellent for nootropic experimentation as well as possible mitigation of MDD (Major Depressive Disorder). As with all pharma aiming to treat depression, mileage may vary, depending on the underlying cause(s) of the disorder.
    I highly recommend Limitless Life. The products are of the highest quality, the prices are low, the people respond quickly to inquiries and have been exceedingly generous on the few occasions where a delivery or other problem arose. A company with a personal touch!

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