VIP: 5mg 99%
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VASOACTIVE INTESTINAL PEPTIDE
What is VIP?
VIP is a neuropeptide with 28 amino acid residues that is widely distributed throughout the central and peripheral nervous systems. VIP has a wide range of biological effects and functions as a neurotransmitter, neuromodulator, and hormone. VIP was first identified as a vasodilator peptide that relaxes smooth muscle in the lung; it was isolated from pig gut in 1970. Its previous title as a “potential gastrointestinal hormone” was quickly replaced with its new, and presumably accurate, identification as a neuropeptide having neurotransmitter and neuromodulator capabilities.
Characteristics of VIP
CAS:37221-79-7
Molecular Formula: C147H237N43O43S
Sequence: HSDAVFTDNYXRLRKQMAVKKYLNSXLN
PubChem CID: 445567960
Synonyms: Vasoactive Intestinal Polypeptide, PHM27
Researched Functionality
VIP has been investigated in many different bodily systems, such as the gastrointestinal, respiratory, cardiovascular, immunological, central, and peripheral neurological systems, and it was discovered that it plays many important functions in each of these systems. It has been difficult to estimate the exact engagement within the system, however, owing to the variety of positions that exist inside the system and the many responsibilities that each plays.
According to research, VIP may help decrease inflammation throughout the body, but it may be especially beneficial for neurological diseases, pulmonary fibrosis, inflammatory bowel disease, and cardiac fibrosis. The peptide seems to possibly be extremely effective in a variety of fibrotic pathways and may give therapeutic advantages in the process of fibrosis that causes so much morbidity and death.
The research indicates VIP potentially can be a strong immune system regulator and a general anti-inflammatory, in addition to its possible antifibrotic properties, which seem to be mediated through anti-inflammatory activities. It has also been shown in the research that the peptide can possibly protect the central nervous system against injury and that its potential to retain cognitive function in the presence of neurodegenerative illness is of great interest.
VIP is highlighted to possibly being effective in multiple organ systems.
Mechanism of action
Due to VIP being so prevalent in the body, it is difficult to pinpoint its precise mechanism of action but here is an idea.
“[VIP] acts on the HPA Axis: the “stress” axis of the hypothalamus, pituitary, and adrenal glands to regulate adrenal hormone production and release. This means everything downstream from the adrenals improves, including cortisol, DHEA (the precursor to sex hormones) and aldosterone, which regulates fluid volume in conjunction with ADH.” (Source)
“VIP stimulates prolactin secretion from the pituitary and catecholamine release from the adrenal medulla In the immune system, VIP regulates T cell traffic and inhibits mitogen-activated proliferation of T cells by inhibiting IL-2 production Other actions of VIP include stimulation of electrolyte secretion and protection against oxidant injury.” (Source)
References:
https://pharmrev.aspetjournals.org/content/56/2/249.abstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743256/
https://en.wikipedia.org/wiki/Vasoactive_intestinal_peptide
https://www.sciencedirect.com/topics/neuroscience/vasoactive-intestinal-peptide
https://selfhacked.com/blog/vip-a-potent-anti-inflammatory-hormone-and-natural-ways-to-increase-it/
Research
VIP Peptide Research
VIP has been investigated in many different bodily systems, such as the gastrointestinal, respiratory, cardiovascular, immunological, central, and peripheral neurological systems, and it was discovered that it plays many important functions in each of these systems. It has been difficult to estimate the exact engagement within the system, however, owing to the variety of positions that exist inside the system and the many responsibilities that each plays.
According to research, VIP may help decrease inflammation throughout the body, but it may be especially beneficial for neurological diseases, pulmonary fibrosis, inflammatory bowel disease, and cardiac fibrosis. The peptide seems to possibly be extremely effective in a variety of fibrotic pathways and may give therapeutic advantages in the process of fibrosis that causes so much morbidity and death.
The research indicates VIP potentially can be a strong immune system regulator and a general anti-inflammatory, in addition to its possible antifibrotic properties, which seem to be mediated through anti-inflammatory activities. It has also been shown in the research that the peptide can possibly protect the central nervous system against injury and that its potential to retain cognitive function in the presence of neurodegenerative illness is of great interest.
VIP is highlighted as possibly being effective in multiple organ systems.
VIP Peptide Structure
CAS Number: 37221-79-7
Molecular Formula: C147H237N43O43S
Sequence: HSDAVFTDNYXRLRKQMAVKKYLNSXLN
PubChem CID: 445567960
Synonyms: Vasoactive Intestinal Polypeptide, PHM27
Source: PubChem
References
https://pharmrev.aspetjournals.org/content/56/2/249.abstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6743256/
https://en.wikipedia.org/wiki/Vasoactive_intestinal_peptide
https://www.prohealth.com/library/vasoactive-intestinal-peptide-vip-treatment-the-key-to-100-recovery-from-mold-ilness-41086
https://www.sciencedirect.com/topics/neuroscience/vasoactive-intestinal-peptide
https://selfhacked.com/blog/vip-a-potent-anti-inflammatory-hormone-and-natural-ways-to-increase-it/
https://pubchem.ncbi.nlm.nih.gov/compound/53314964/
FAQ
What is VIP (Vasoactive Intestinal Peptide)?
VIP is a neuropeptide with 28 amino acid residues that is widely distributed throughout the central and peripheral nervous systems. VIP has a wide range of biological effects and functions as a neurotransmitter, neuromodulator, and hormone.
VIP was first identified as a vasodilator peptide that relaxes smooth muscle in the lung; it was isolated from pig gut in 1970. Its previous title as a “potential gastrointestinal hormone” was quickly replaced with its new, and presumably accurate, identification as a neuropeptide having neurotransmitter and neuromodulator capabilities.
How Does VIP Peptide Work?
VIP, also known as Vasoactive Intestinal Peptide, serves a critical role in the body’s regulatory processes. Primarily, VIP helps in the regulation of smooth muscle activity, secretion of water into pancreatic juices and sweat, and the release of hormones from the pituitary gland. Furthermore, it helps in regulating the dilation and constriction of blood vessels. The effective role of VIP extends to neuroprotective functions as well. It maintains a balancing act within the body, controlling essential biological activities and promoting overall well-being.
What are the Benefits of VIP Peptide?
VIP peptide, or Vasoactive Intestinal Peptide, confers multiple benefits. It can stimulate cell proliferation, which aids in the processes of growth, healing, and regeneration. VIP plays a critical role in maintaining our circadian rhythm, leading to regulated sleep patterns and overall better health. Furthermore, it can help to control autoimmune disorders by regulating immune responses. Its anti-inflammatory effects contribute to improved blood flow, reducing the risk of related health issues.
Where to Buy VIP
Vasoactive Intestinal Peptide (VIP) is primarily available through specialized online retailers, such as Limitless Life Nootropics. VIP is typically sold for laboratory and research purposes.
How does VIP affect the gastrointestinal tract?
VIP plays a crucial role in the gastrointestinal (GI) tract. It helps in the secretion of water and electrolytes, regulates acid secretion, and promotes smooth muscle relaxation. It also has anti-inflammatory effects in the GI tract.
What are the effects of VIP on blood vessels?
VIP has vasodilatory effects on blood vessels, meaning it can widen the blood vessels and increase blood flow. This can have several beneficial effects in different physiological processes.
Can VIP help with inflammatory bowel disease?
Yes, VIP is known to have anti-inflammatory effects in the gastrointestinal tract, including inflammatory bowel disease. It helps in reducing inflammation and promoting healing in the affected areas.
How does VIP affect the immune response?
VIP has immunomodulatory effects and can influence immune cells and their responses. It helps regulate the immune response and has both anti-inflammatory and anti-autoimmune properties.
Can VIP be used as a treatment?
VIP has been studied for its potential therapeutic uses. It can be used in nasal sprays for certain conditions, and research suggests that it may have benefits in treating various inflammatory and autoimmune disorders.
How is VIP produced in the body?
VIP is produced by certain cells in the nervous systems, including neurons and immune cells. It is generated as a precursor molecule that is later processed into its active form.
What is the role of the VIP receptor?
The vasoactive intestinal peptide receptor is a receptor protein that binds to VIP molecules. It is involved in transmitting the signals of VIP and mediating its effects on target cells and tissues.
What are the anti-inflammatory effects of VIP?
VIP has potent anti-inflammatory effects. It can inhibit the release of pro-inflammatory cytokines, reduce the recruitment of immune cells to inflamed areas, and regulate inflammatory processes.
Legal Disclaimer
This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.
Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.
The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.
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