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Tirzepatide HA 10mg (1 x 10mg)

Original price was: $274.99.Current price is: $214.99.

Container

Glass Vial

Presentation

Solid Crystals

Container

Glass Vial

Presentation

Solid Crystals

In Stock

Reference Standard 99%+

Looking for 98.5% or Pure versions?

 

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Research

Tirzepatide Fact Sheet

Molecular formula: C225H348N48O68
Molecular weight:
4813.45
Purity: 99%+
CAS Number 2023788-19-2
Research Applications:
  • Type 2 Diabetes
  • Weight Loss

Tirzepatide Research Overview

Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that has shown promise in the management of type 2 diabetes (T2D). It received regulatory approval from the U.S. Food and Drug Administration in May 2022 and from the European Commission in September 2022.

Tirzepatide and Type 2 Diabetes

In the phase 3 clinical development program, known as SURPASS, tirzepatide demonstrated superior glycemic and body weight control compared to placebo and active comparators across a range of patients with T2D. The drug has been hailed as the most potent glucose and body weight lowering agent available for the management of T2D.

Tirzepatide’s hypoglycemic and weight loss effects have been demonstrated in several large clinical trials. It has also shown potential for cardiovascular protection, which is particularly beneficial for individuals with T2D who are at risk for or have established cardiovascular disease or heart failure.

In addition to its clinical efficacy, tirzepatide has been well-received by patients. Exit interviews from clinical trials highlighted the meaningful impact of the drug on patients’ quality of life, particularly in relation to weight loss.

The potential of tirzepatide to improve cardiovascular outcomes is currently being assessed in a cardiovascular outcomes trial (SURPASS CVOT), with results expected in 2024. Tirzepatide is also being explored for its potential in other areas such as non-alcoholic fatty liver disease (NAFLD), renal, and neuroprotection.

Tirzepatide and Weight Loss

In terms of weight management, tirzepatide has shown promising results in clinical trials. It has demonstrated significant reductions in body weight in patients with T2DM, with weight loss of 15 to 20% compared to baseline being plausible in the short term. The weight loss effects of tirzepatide are notable, as obesity is a major risk factor for the development of T2DM and cardiovascular diseases. Although reduced food intake stimulated by tirzepatide is considered to be the main contributor to the reduced body weight, other mechanisms, including increased energy expenditure induced by tirzepatide, may also contribute to the reduced body weight and liver fat content.

In addition to its glucose-lowering and anti-obesity effects, tirzepatide has been reported to have potential cardiovascular benefits. It has been shown to improve lipid profiles in clinical studies, lowering total cholesterol, low-density lipoprotein cholesterol, and triglycerides, and significantly increasing high-density lipoprotein cholesterol. Furthermore, a study across the SURPASS 1-5 clinical trials found that tirzepatide-induced systolic blood pressure reduction was primarily mediated through weight loss.

FAQ

What is Tirzepatide?

Tirzepatide is a novel medication that has been approved by the FDA for the treatment of type 2 diabetes mellitus. It is a synthetic peptide and a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist, composed of 39 amino acids. Functionally, it stimulates insulin release from the pancreas, leading to a reduction of hyperglycemia. In addition to its glucose-lowering effects, tirzepatide has been noted for its potent weight loss properties, making it a potential treatment for obesity as well.

How Does Tirzepatide Work?

Tirzepatide is a synthetic peptide and a dual gastric inhibitory polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) receptor agonist. It is composed of 39 amino acids and is an analog of the gastric inhibitory polypeptide. Tirzepatide acts by stimulating insulin release from the pancreas, leading to a reduction of hyperglycemia. It also increases the levels of adiponectin, a protein hormone that modulates several metabolic processes, including glucose regulation and fatty acid oxidation.

Tirzepatide activates the GLP-1R signaling pathway to stimulate glucose-dependent insulin secretion through activity at the GIP receptor (GIPR) or the GLP-1R. It works to stimulate first- and second-phase insulin secretion, and reduces glucagon levels, both in a glucose-dependent manner. Tirzepatide also transiently delays gastric emptying, lowers fasting and postprandial glucose concentration, decreases food intake, and reduces body weight in patients with type 2 diabetes.

Is Tirzepatide the Same as Mounjaro?

Tirzepatide and Mounjaro are the same medication. Tirzepatide is the active ingredient in Mounjaro, an antidiabetic medication used for the treatment of type 2 diabetes and for weight loss.

Has Tirzepatide Been Studied for Insulin Secretion?

Tirzepatide stimulates insulin secretion in a glucose-dependent manner, which is a crucial action for lowering blood glucose in patients with type 2 diabetes. It works to stimulate both first- and second-phase insulin secretion and reduces glucagon levels.

In a study, tirzepatide significantly improved the clamp disposition index, which combines measures of insulin secretion and sensitivity, compared to a placebo. This improvement was also significantly greater than with semaglutide, another GLP-1 receptor agonist. The study found significant improvements in total insulin secretion rate and insulin sensitivity for tirzepatide versus semaglutide.

Has Tirzepatide Been Shown to Lower Blood Sugar Levels?

Tirzepatide has been shown to lower blood sugar levels. It has demonstrated improved glycemic control and substantial weight loss in patients with type 2 diabetes in phase 3 trials.

Where to Buy Tirzepatide Online?

Tirzepatide can be purchased online from reputable biotech suppliers such as Limitless Life Nootropics. Limitless Life offers a wide selection of research-grade peptides for sale online for scientific research and development purposes.

Our extensive range of products undergoes rigorous third-party testing to verify the sequential signatures of all research peptides for sale. With our commitment to quality, most orders are promptly sent out on the same day they are placed, accompanied by our unwavering dedication to providing exceptional customer service.

COA

Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide Certificate of Analysis for Tirzepatide

Legal Disclaimer

This product is sold as a pure compound for research purposes only and is not meant for use as a dietary supplement. Please refer to our terms and conditions prior to purchase.

Safety Information: Keep this product out of the reach of children. This material has limited research available about it and may result in adverse effects if improperly handled or consumed. This product is not a dietary supplement, but a pure substance, sold as a raw material. We attest exclusively to the quality, purity and description of the materials we provide. This product is for use and handling only by persons with the knowledge and equipment to safely handle this material. You agree to indemnify us for any adverse effects that may arise from improper handling and/or consumption of this product.

The articles and information on products that may be found on this website are provided exclusively for the purposes of providing information and education. These items are not pharmaceuticals or medications, and the Food and Drug Administration has not given permission for the treatment or prevention of any disease, medical condition, or ailment using them.

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