Research
PT-141 Peptide Information
| Molecular formula: | C50H68N14O10 |
| Molecular weight: |
1025.2Â g/mol
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| PubChem CID: |
16130571
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| Synonyms |
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| Research Applications: |
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PT-141 Overview
PT-141, also known as Bremelanotide, is a synthetic peptide that has been explored for its potential therapeutic applications, particularly in the treatment of sexual dysfunction. The research into PT-141 has revealed its promising effects in both male and female sexual health, which can be categorized into two main areas of benefits.
Treatment of Erectile Dysfunction (ED) and Sexual Arousal in Males
PT-141 has been shown to have erectogenic properties, meaning it can induce penile erections. This effect is thought to be due to its action on melanocortin receptors in the central nervous system, particularly in the hypothalamus. Clinical studies, including Phase II trials, have supported the use of PT-141 as a therapy for erectile dysfunction, demonstrating its effectiveness in improving erectile function [R].
Promotion of Sexual Desire and Arousal in Females
Preliminary clinical data suggest that PT-141 can also promote sexual desire and arousal in women. This is significant because it addresses a gap in treatment options for female sexual dysfunction, which has fewer therapeutic options compared to male sexual dysfunction. The mechanism is similar to that in males, with PT-141 acting on central nervous system receptors to evoke responses analogous to sexual arousal [R].
