Description: Oxytocin
PubChem CID
439302
Molecular Formula
C43H66N12O12S2
Synonyms
OXYTOCIN
50-56-6
Pitocin
Endopituitrina
Ocytocin
Molecular Weight
1007.2 g/mol
Sequence
CYIQNCPLG
Description
Oxytocin is a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain; the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary. Together with the neuropeptide vasopressin, it is believed to influence social cognition and behaviour. It has a role as an oxytocic and a vasodilator agent. It is a peptide hormone and a heterodetic cyclic peptide.
ChEBI
Sir Henry H. Dale first identified oxytocin and its uterine contractile properties in 1906. Like all other neurohypophysial hormones, oxytocin is composed of nine amino acids with a disulfide bridge between the Cys 1 and 6 residues. In the mid-1950s, synthetic oxytocin was successfully synthesized by a biochemist named Vincent du Vigneaud; he was later recognized with a Nobel prize for his work. Oxytocin continues to be an important tool in modern obstetrics to induce labor when indicated and to manage postpartum hemorrhage. It is estimated that labor induction with oxytocin is used in almost 10% of deliveries globally. It should be noted that there are risks associated with oxytocin intervention during childbirth. Oxytocin should be used judiciously only when necessary and by experienced healthcare practitioners. Although most commonly linked to labor and delivery, oxytocin actually has broad peripheral and central effects. It plays an important role in pair bonding, social cognition and functioning, and even fear conditioning. Oxytocin also serves a role in metabolic homeostasis and cardiovascular regulation.
Oxytocin in vial form, specifically prepared for “research purposes only,” is an exceptional product designed to support various scientific explorations. Oxytocin, often referred to as the ‘love hormone,’ is a hormone and neuropeptide involved in social bonding, sexual reproduction, and during and after childbirth (1).
Oxytocin is synthesized in the hypothalamus and secreted by the posterior pituitary gland. It is known to play a key role in social behavior and bonding, participating in intricate neurological processes that facilitate human connection and relationships (2). This makes oxytocin a captivating subject of study for neuroscientists and social psychologists.
The product’s role in social bonding isn’t its only area of interest. It has been established that oxytocin plays a crucial role during and after childbirth, stimulating uterine contractions and lactation. This makes it a focal point of interest in obstetrics and neonatology research (3).
Moreover, oxytocin is also implicated in facilitating trust and bonding between individuals. It’s been dubbed the “trust hormone” due to its effects on behavior, including its role in enhancing feelings of empathy and reducing fear and anxiety (4). This positions it as a fascinating subject of research in psychology and psychiatry.
In addition, there’s an evolving body of research focusing on the anxiolytic (anxiety-reducing) properties of oxytocin. Studies have shown that it may help modulate the stress response and potentially mitigate symptoms of anxiety disorders, making it an area of focus in neuropsychology and pharmacology (5).
Our Oxytocin product is produced through a rigorous process that ensures its purity and stability. It is synthesized through solid phase peptide synthesis (SPPS), a process that allows for high accuracy and control over the peptide sequence (6).
Our oxytocin in vial form for research purposes is available in a lyophilized form. This ensures long-term stability and ease of storage, while also allowing for precision in reconstitution for various experimental setups.
Every batch of our product undergoes rigorous quality control tests. We verify the purity, potency, and identity of each batch to maintain consistent high quality. This ensures reliability of results across multiple experiments.
Our oxytocin product offers a wide range of research applications. Whether your studies involve neurobiology, psychology, obstetrics, or pharmacology, our oxytocin in vial form can serve as a robust tool for your research needs.
In conclusion, our Oxytocin in vial form is a valuable tool for scientific research. With its diverse range of biological effects and its pivotal role in human health and behavior, this product may help you unlock new discoveries and deepen your understanding of the human body and mind.
References:
(1) Gimpl, G., & Fahrenholz, F. (2001). The Oxytocin Receptor System: Structure, Function, and Regulation. Physiological Reviews, 81(2), 629–683. https://doi.org/10.1152/physrev.2001.81.2.629
(2) Meyer-Lindenberg, A., Domes, G., Kirsch, P., & Heinrichs, M. (2011). Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine. Nature Reviews Neuroscience, 12(9), 524–538. https://doi.org/10.1038/nrn3044
(3) Kim, S., Soeken, T. A., & Crombleholme, W. R. (2000). Oxytocin for labor induction. Clin Obstet Gynecol, 43(3), 489-94. https://doi.org/10.1097/00003081-200009000-00009
(4) Zak, P. J., Stanton, A. A., & Ahmadi, S. (2007). Oxytocin Increases Generosity in Humans. PLoS ONE, 2(11), e1128. https://doi.org/10.1371/journal.pone.0001128
(5) Neumann, I. D., & Slattery, D. A. (2016). Oxytocin in General Anxiety and Social Fear: A Translational Approach. Biological Psychiatry, 79(3), 213–221. https://doi.org/10.1016/j.biopsych.2015.06.004
(6) Stewart, J.M., Young, J.D. (1984). Solid Phase Peptide Synthesis. Pierce Chemical Company.