This is the acetylated version of Selank. It crosses the blood brain barrier easier than the original form of Semax and therefore is more potent by weight. This bottle provides roughly 100, 100mcg sprays. We are shipping peptide in a separate glass vile to insure potency for customers who don’t get overnight shipping or are outside of the USA. Spray bottle will be included.
Contents: N-Acetyl Selank, Verified by HPLC to exceed 98.92% purity.
Research
N-acetyl Selank Research
N-Acetyl Selank is a modified form of the peptide Selank, a nootropic and anxiety-reducing peptide. N-Acetyl Selank Amidate can be considered as an improved form of Selank, as studies have revealed that it enhances every aspect of Selank by boosting its strength, duration of action, absorption rate and ability to cross the blood-brain barrier.
Below are some key findings from research conducted on N-Acetyl Selank:
- Higher Potency: N-Acetyl Selank Amidate exhibits greater potency compared to standard Selank as a result of its enhanced ability to efficiently cross the blood-brain barrier
- Gene Expression: Selank has been shown to modify gene expression in the brain, reducing the effects of the neurotransmitter GABA, altering cell membrane permeability, and enhancing production of brain-derived neurotrophic factor (BDNF)
- Anxiolytic and Nootropic Effects: Selank has pronounced anxiolytic activity and acts as a stable neuropsychotropic, antidepressant, and antistress drug that relieves aggression and fear reaction in different animal species. It also has a nootropic action, which positively influences the formation of memory and learning processes. N-Acetyl Selank has been shown to regulate the body’s stress response, which is critical for improving mood and memory
- Immunomodulatory Effects: Selank has marked immunomodulatory activity
N-acetyl Selank Structure
PubChem CID: 11765600
Molecular Formula: C33H57N11O9
Molecular Weight: 159.21
Synonyms: 129954-34-3, TP-7, Thr-Lys-Pro-Arg-Pro-Gly-Pro, L-Proline, L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-Selanc
Source: PubChem
Selank and Anxiety
Selank alters the function of GABA synapses that are involved in calming the nervous system. By enhancing GABA’s inhibitory effects on other neurotransmitters, Selank can effectively alleviate anxiety. Furthermore, Selank has the ability to influence interleukin-6 (IL-6), resulting in a decrease in its levels and providing anti-inflammatory properties.
Studies have shown that Selank has anxiolytic properties and can also provide stimulation. It has been researched in Russia as a potential treatment for generalized anxiety disorder (GAD) and neurasthenia. The anxiolytic effects of Selank were found to be comparable to those of medazepam, while also exhibiting antiasthenic and psychostimulant effects.
Selank and Memory
Selank has been discovered to enhance memory stability in rats, irrespective of their anxiety levels. This suggests that the peptide has effects that go beyond alleviating stress-related memory impairment. Selank seems to impact memory by modulating the expression of certain genes in the hippocampus. In a study, rats with neurological impairment experienced cognitive restoration when treated with Selank.
In a study conducted on Wistar rats, it was discovered that Selank demonstrated the ability to enhance memory retention for a duration of 30 days following a single injection. Additionally, Selank was observed to stimulate serotonin metabolism in the hypothalamus and caudal brain stem for a period ranging from 30 minutes to 2 hours.
References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757669/
https://pubmed.ncbi.nlm.nih.gov/18454096/
https://www.sciencedirect.com/science/article/abs/pii/S0924933812752811
https://pubmed.ncbi.nlm.nih.gov/20919548/
https://pubmed.ncbi.nlm.nih.gov/18683497/
https://www.frontiersin.org/articles/10.3389/fphar.2016.00031/full
FAQ
What is Selank?
Selank is a synthetic peptide drug developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It is composed of seven amino acids, with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro.
Selank is designed to mimic the effects of human tuftsin. It is known for its nootropic and anxiolytic properties, and has been found to impact the expression of Interleukin-6 (IL-6) and influence the balance of T helper cell cytokines.
How Does Selank Work?
Selank primarily functions by modulating neurotransmitter levels in the brain, specifically serotonin, dopamine, and gamma-aminobutyric acid (GABA). These neurotransmitters are essential for regulating mood, anxiety, and various cognitive functions.
What are the Benefits of Selank?
Selank is a synthetic analog of the endogenous tuftsin molecule that has been shown to have several benefits. Here are some of the benefits of Selank:
- Reduced anxiety and depression
- Improved learning and memory
- Enhanced cognitive function
- Improved immune response
- Improved mood and sleep
Where to Buy Selank
Limitless Life Nootropics is the leading online source for purchasing Selank. Our extensive range of products undergoes rigorous third-party testing to verify the sequential signatures of all peptides available for sale. This meticulous process ensures that customers consistently receive pharmaceutical-grade products of the utmost purity. With our commitment to quality, most orders are promptly sent out on the same day they are placed, accompanied by our unwavering dedication to providing exceptional customer service.