Ipamorelin
is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue and immune cells. Unlike other GH releasing peptides, ipamorelin only stimulates GH release in a manner very similar to that of growth hormone releasing hormone.
CAS:Â 170851-70-4
Molecular Formula:C38H49N9O5
Sequence: XHXFK
Great resources for reading:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108996/
https://www.ncbi.nlm.nih.gov/pubmed/10373343
https://www.ncbi.nlm.nih.gov/pubmed/9849822
https://clinicaltrials.gov/ct2/show/NCT01280344
CJC1295 Without DAC
Also know as, Mod GRF 1-29 is a synthetic analogue of growth hormone-releasing hormone and a growth hormone secretagogue which was developed by ConjuChem Biotechnologies. It is a modified form of GHRH with improved pharmacokinetics, especially in regard to half-life. Wikipedia
Molecular Formula: C152H252N44O42
CAS: 446262-90-4
Sequence: YADAXFXQSYRKVLAQLSARKLLQDXLSR
Great resources for reading:
https://academic.oup.com/jcem/article/91/3/799/2843281
https://www.ncbi.nlm.nih.gov/pubmed/16352683
