Research
GHK-Cu Fact Sheet
| Molecular formula: |
C17H33N5O4 |
| Molecular weight: |
371.5 g/mol |
| Purity: |
99% |
| Sequence: |
glycyl-l-histidyl-l-lysine |
| Research Applications: |
- Wound healing
- Antioxidant
- Anti-inflammatory
- Skin rejuvenation
- Hair growth
|
GHK-Cu (Copper Peptide) Overview
GHK-Cu, also known as copper peptide GHK-Cu, is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. It was first isolated from human plasma and has since been found in other areas of the body, such as saliva and urine. Copper peptides are naturally occurring protein fragments that have a strong attraction to copper ions and are thought to play a vital role in the normal functioning of the body. GHK-Cu has been the subject of numerous studies, which have revealed several roles and benefits in the human body.
GHK-Cu and Wound Healing
GHK-Cu has been shown to improve the healing of ischemic open wounds in rats, leading to faster healing. It stimulates the synthesis of collagen, elastin, and glycosaminoglycans in the skin, which are essential for wound healing. In the same study, wounds treated with GHK-Cu showed a decreased concentration of metalloproteinases 2 and 9, which are enzymes involved in the breakdown of extracellular matrix during the wound healing process.
GHK-Cu stimulates collagen and decorin production, which are essential for tissue regeneration and wound healing. It also increases cellular stemness and secretion of trophic factors by mesenchymal stem cells. GHK-Cu also promotes skin remodeling, which is crucial for wound healing and regeneration.
GHK-Cu Antioxidant and Anti-Inflammatory Effects
GHK-Cu (glycyl-l-histidyl-l-lysine copper) has been shown to have antioxidant and anti-inflammatory effects in various studies. GHK-Cu may prevent oxidative stress in the skin by regulating copper levels and influencing the activity of various antioxidant genes.
GHK-Cu has also been shown to ameliorate lipopolysaccharide-induced acute lung injury in mice by suppressing inflammation and reducing oxidative damage.
GHK-Cu and Skin Remodeling and Regeneration
GHK-Cu has been shown to improve the appearance of aging skin in clinical studies. Both GHK and GHK-Cu have been found to have anti-inflammatory and tissue remodeling properties.
GHK-Cu at a 1nM concentration
enhances the expression of basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF) in human dermal fibroblasts exposed to radiation. These factors promote the formation of blood vessels and improve blood flow to injured tissues. The ability of GHK and its Cu chelate to promote skin remodeling, wound healing, and regeneration, and its prominent antioxidant and anti-inflammatory effects are qualities that help with healthy aging.
GHK-Cu and Promotion of Blood Vessel Growth
GHK-Cu has demonstrated the ability to stimulate blood vessel and nerve growth, enhance the production of collagen, elastin, and glycosaminoglycans, and aid in the functioning of different tissues.
Copper plays a crucial role in stimulating the growth of blood vessels and acts as a necessary co-factor in the signaling processes involved in angiogenesis. The combination of GHK-Cu with copper (II)
has been found to dramatically increase cell proliferation, differentiation, and production in a synthetic cryogel extracellular matrix (ECM) model.
GHK-Cu and Hair Growth
GHK-Cu has been found to increase hair growth and thickness, as well as enlarge hair follicle size. GHK-Cu stimulates collagen synthesis by fibroblasts, which is necessary for hair growth and thickness.
GHK-Cu promotes the growth of human hair follicles by stimulating the proliferation and precluding the apoptosis of dermal papilla cells (DPCs). GHK-Cu has strong inhibitory effects on dihydrotestosterone (DHT), which is a key factor in hair loss regulation.
FAQ
What is GHK-Cu?
GHK-Cu, also known as copper peptide GHK-Cu, is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. It occurs naturally and was initially discovered in human plasma. It can also be found in saliva and urine. GHK-Cu has been extensively studied and has shown the ability to regulate the expression of many human genes, often restoring gene expression to a more favorable state.
Synthetic GHK-Cu is used in various cosmetic products, such as serums and creams, to provide benefits to the skin. Additionally, GHK-Cu has shown potential in peptide therapy for growth hormone, hair and skin, weight loss, immune system support, repair, neurogenic/neurorestorative, muscle building, libido, endocrine regulation, and sexual health.
What are the Benefits of Copper Peptide GHK-Cu?
GHK-Cu has numerous benefits for skin rejuvenation. It promotes skin remodeling, improves firmness, skin elasticity, and overall appearance, and reduces wrinkles. It also repairs protective skin barrier proteins, enhances skin structure, and smooths rough skin. Additionally, it stimulates collagen production, promotes the growth of new blood vessels and nerves, and aids in the healing process for wounds. When used topically, GHK-Cu may also improve hair growth and thickness.
In terms of wound healing, GHK-Cu has regenerative and protective actions that can improve the healing of open wounds. It also reduces inflammation, fights against free radicals, and aids in overall wound healing.
GHK-Cu has neurogenic and neurorestorative properties, promoting nerve outgrowth and supporting nervous system function. This can be beneficial for addressing various neurological conditions and maintaining optimal neural health.
With its antioxidant and anti-inflammatory effects, GHK-Cu helps slow the effects of aging on the skin, including improving elasticity and overall skin health.
Furthermore, GHK-Cu has been shown to offer benefits such as endocrine regulation and sexual health improvements as part of peptide therapy.
Where to Buy GHK-Cu
GHK-Cu can be purchased online from a reputable peptide supplier, such as Limitless Life Nootropics. It is important to ensure you are purchasing from a trustworthy source to guarantee the quality and authenticity of the product.
