Research
Epitalon Research
Epitalon, a synthetic peptide, was initially identified in the latter part of the 1980s by Professor Vladimir Khavinson of The Sankt Petersburg University in Russia. It is recognized as a telomerase activator and potential anti-aging drug considered to be the likely active ingredient in an extract from the bovine pineal gland known as epithalamin.
Epitalon is a tetrapeptide and consists of the amino acid sequence Ala-Glu-Asp-Gly, having the molecular arrangement of C14H22N4O9. Studies suggest that Epitalon triggers the activity of genes and the production of proteins during neurogenesis, potentially through an epigenetic process. It seems to intensify the multiplication of lymphocytes in the thymus, theoretically enhancing the generation of interferon gamma by T-cells. Additionally, Epitalon has demonstrated it extends the lifespan of cells by overcoming the Hayflick division limit.
Epitalon Structure
PubChem CID: 219042
Molecular Formula: C14H22N4O9
Molecular Weight: 390.35
Synonyms: 307297-39-8, Epithalon, Epithalone, Ala-Glu-Asp-Gly
Epitalon and Anti-Aging
Epitalon is a synthetic form of the tetrapeptide epithalamin, which is naturally produced in the pineal gland. It possesses qualities that can slow down the aging process and is recognized as a telomerase activator. Telomerase is a component found in our DNA that safeguards and enables the replication of DNA, facilitating the regeneration of aging cells and the formation of new cells in the body.
Studies have demonstrated that Epitalon has the ability to diminish age-related alterations in the immune and neuroendocrine systems, thereby lowering the likelihood of developing chronic illnesses. Furthermore, it has been discovered that Epitalon possesses remarkable antioxidant properties, which may contribute to promoting longevity.
Research has been carried out on both mice and humans, and the most definitive outcomes of Epitalon in humans have been determined as:
- Elongation of telomeres due to Epitalon action
- Anti-aging
- Telomerase activation
Extensive clinical research has demonstrated numerous favorable outcomes in middle-aged and elderly individuals, with no documented adverse reactions. Epitalon has also been observed to effectively deter premature cell aging and hinder the growth of tumors in bodily cells.
Epitalon and Skin Health
Epitalon has been proven to promote the production of collagen, enhancing skin firmness and reducing the visibility of wrinkles and fine lines. Additionally, epitalon may assist in shielding against UV rays and speeding up the recovery of damaged skin cells. By entering the cells, epitalon stimulates the growth and progress of fibroblasts, which release proteins like collagen. This leads to a more significant impact, causing skin rejuvenation on multiple levels.
References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037223/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037278/
