Research
CJC-1295 Peptide Structure
| Molecular formula: | C152H252N44O42 |
| Molecular weight: | 3367.9 g/mol |
| PubChem CID: | 91976842 |
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Mod GRF 1-29 (CJC-1295 Without DAC) Research
Mod GRF 1-29, also known as CJC-1295 without DAC, is a synthetic peptide that mimics growth hormone-releasing hormone (GHRH). It’s a modified version of the original GRF 1-29, with four amino acid substitutions that enhance its stability and effectiveness. This peptide works by binding to GHRH receptors in the pituitary gland, stimulating the natural pulsatile release of growth hormone and increasing insulin-like growth factor 1 production.
Unlike its counterpart with DAC (Drug Affinity Complex), this version has a shorter half-life, making it more suitable for research focused on pulsatile hormone release. Studies have explored its potential for muscle growth, improving metabolism, and supporting recovery processes.
CJC-1295 and Growth Hormone Release
Research has shown that CJC-1295 effectively stimulates growth hormone release by activating the growth hormone-releasing factor (GRF) receptor on the anterior pituitary gland. In studies conducted on rats, CJC-1295 demonstrated a significant increase in GH levels, with a 4-fold increase in the area under the curve over a 2-hour period compared to other GRF analogs [R].
An increase in growth hormone levels may contribute to various potential applications, such as improved muscle mass, reduced body fat, accelerated recovery from injuries, and better overall physical performance. However, these potential research areas are largely based on theoretical understanding and anecdotal evidence rather than extensive clinical trials.
