Cardiogen Information
| Molecular formula: | C18H31N7O9 |
| Molecular weight: | 489.5 g/mol |
| PubChem CID: | 156613454 |
| Synonyms | Â SCHEMBL3194515 |
| Research Applications: |
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Cardiogen Bioregulator Peptide
Cardiogen is a synthetic tetrapeptide that has been studied for its potential effects on cardiovascular function and tissue repair.
Structure and composition:
- Cardiogen has the amino acid sequence H-Ala-Glu-Asp-Arg-OH (AEDR)
- Synthetic tetrapeptide with the molecular formula C18H31N7O9 and molecular weight of 489.5 g/mol
Potential applications and mechanisms:
- Cardiogen is considered a bioregulator peptide that may affect fibroblasts, which are cells involved in tissue repair and scar formation
- Studies suggest it may stimulate proliferation of cardiac cells while inhibiting fibroblast activity
- It may reduce expression of p53 protein, potentially inhibiting apoptosis in cardiac tissue
- Research indicates it could promote regeneration of damaged heart muscle by stimulating cardiac progenitor cells
Areas of research:
- Cardiovascular diseases and heart function
- Tissue repair and regeneration
- Cancer, particularly effects on tumor cell apoptosis
- Prostate health and prostate cancer
Key findings from studies:
- Showed stimulating effects on cell proliferation in heart tissue from young and old rats [R]
- Demonstrated potential tumor-inhibiting effects in rat models of sarcoma [R]
- May regulate signaling factors in prostate fibroblasts [R]
Potential research applications:
- Treatment of heart conditions like heart attack, hypertension, heart failure
- Tissue regeneration and repair
- Cancer research, especially for certain sarcomas
