Research
5-Amino-1Q Fact Sheet
| Molecular formula: | C10H11N2+ |
| Molecular weight: | 159.21 g/mol |
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5-Amino-1MQ Peptide Research
5-Amino-1MQ powder is a refined, research-grade compound designed for use in laboratory settings. It is a potent inhibitor of the enzyme NNMT, which plays a critical role in energy metabolism and fat storage within the body. By inhibiting NNMT, 5-Amino-1MQ powder can modulate the methylation potential of cells and influence the metabolic pathways associated with obesity and type 2 diabetes.
5-Amino 1MQ and NNMT Inhibition
5-Amino 1MQ targets and inhibits NNMT, an enzyme predominantly active in fat tissue and linked to obesity and type 2 diabetes. By blocking NNMT, 5-Amino 1MQ disrupts the enzyme’s role in metabolism and energy homeostasis, presenting a unique opportunity to study these processes in detail [R]
Weight Loss and Obesity Management
Studies have shown that NNMT inhibition by compounds like 5-Amino-1MQ can lead to a reduction in fat mass and improvement in insulin resistance. This is particularly relevant for obesity research, as NNMT levels are often elevated in adipose tissue of obese individuals. The inhibition of NNMT by 5-Amino-1MQ may therefore represent a novel approach to weight loss intervention [R].
Metabolic Regulation
5-Amino-1MQ has been associated with beneficial metabolic changes, including improved insulin sensitivity and altered lipid metabolism. This is supported by metabolomic profiling studies that have identified complex lipid species and amino acid analogues associated with the response to weight loss interventions [R].
NNMT Inhibition and Microbiome Alteration
Research indicates that NNMT inhibition can establish a distinct microbiome profile. This is significant as the gut microbiota has been implicated in the pathogenesis of metabolic diseases. A study on diet-induced obese (DIO) mice demonstrated that a reduced-calorie diet combined with NNMT inhibition resulted in a unique microbiome composition, suggesting potential applications for 5-Amino-1MQ in gut microbiota-related metabolic research [R].
Enhanced Metabolic Understanding
The use of 5-Amino-1MQ in research can provide deeper insights into the metabolic pathways involved in obesity and related conditions. This can aid in the development of targeted therapies and personalized medicine approaches for metabolic disorders.
