Research
5-Amino-1MQ Research
5-Amino-1MQ is a small molecule drug that functions to block the activity of an enzyme called nicotinamide N-methyltransferase (NNMT). It has been studied for its potential in weight loss and improvements in obesity-related conditions.
5-Amino-1MQ Structure
PubChem CID: 950107
Molecular Formula: C10H11N2+
Molecular Weight: 159.21
Synonyms: 5-amino-1-methylquinolinium, SCHEMBL6403148, CHEMBL4116828, ZINC552049, STL196667
Source: PubChem
5-Amino-1MQ and Weight Loss
5-Amino-1MQ is a type of peptide that has been shown to aid in weight loss by inhibiting a certain enzyme known as nicotinamide N-methyltransferase (NNMT). This particular enzyme has a connection to obesity and type 2 diabetes, and studies indicate that 5-Amino-1MQ can curb its production, which could potentially prevent the buildup of fat. Some of the benefits of 5-amino-1MQ for weight loss include:
- Decrease in weight gain
- Reduction in fat mass
- Increase in energy
- Maintenance of muscle mass
- Improvement in obesity-linked commodities
Clinical studies have shown that 5-amino-1MQ may be effective for weight loss in those with severe obesity. In addition, a study showed that treatment with an NNMT inhibitor (5-amino-1-methylquinolinium) combined with a low-fat diet promoted weight loss. Another study showed that an NNMT inhibitor caused weight loss and reduced adipose tissue mass in mice.
Overall, 5-amino-1MQ is a promising peptide for weight loss that may help those with severe obesity and prevent fat accumulation.
References:
https://www.nature.com/articles/s41598-021-03670-5
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826726/
5-Amino-1MQ and Bodybuilding
5-Amino-1MQ is a peptide molecule derived from methylquinolinium (MQ) that aids in muscle development and weight loss. As a selective membrane-permeable molecule, it obstructs the NNMT enzyme activity, helping in fat burning for energy while preserving muscle tissue. Here are some potential benefits of 5-Amino-1MQ for bodybuilding:
- Weight Loss: 5-Amino-1MQ enables the body to burn fat for energy, which can help with weight loss. It can also prevent fat accumulation and may be a better treatment option for someone with type 2 diabetes and other conditions related to obesity.
- Muscle Building: 5-Amino-1MQ can trigger muscle tissue growth and act synergistically with workout regimens. It can stimulate stem cell production, which can help in healing injuries and prevent muscle wasting.
- Body Recomposition: 5-Amino-1MQ can help achieve body recomposition goals without drastically changing training programs or diets. It can help build lean muscle while shredding fat at the same time.