Research
5-Amino-1Q Fact Sheet
Molecular formula: | C10H11N2+ |
Molecular weight: | 159.21Â g/mol |
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Research Applications: |
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5-Amino-1MQ Capsules Research
5-Amino-1MQ is a small molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). Research has shown that it has the potential to reverse diet-induced obesity and related type 2 diabetes (T2D) without significant impact on food intake or observable adverse effects.
In vitro studies have demonstrated that 5-amino-1MQ has high cell permeability, enzyme selectivity, and cell culture efficacy. It has also been found to prevent fat accumulation and shrink fat cells, resulting in less fat tissue. The molecule is being explored as a promising and innovative approach in the field of health and wellness, particularly in relation to weight management, muscle health, and overall well-being.
5-Amino-1MQ and Weight Loss
5-Amino-1MQ is a small, selective, and membrane-permeable molecule that has been recognized for its potential in weight loss and wellness. It functions by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT), which is associated with obesity and the storage of fat. By blocking NNMT, 5-Amino-1MQ can contribute to the reduction of body fat and facilitate weight loss.
Research has suggested that 5-Amino-1MQ increased levels of intracellular NAD+, which is indispensable for the process of energy creation within cells, particularly during physical activity. By increasing the amount of NAD+ in the body, cells can burn fat more effectively and efficiently. NNMT inhibition also means the body is less prone to storing fat, thereby contributing to weight loss [R].
In vivo studies have shown that treatment with 5-Amino-1MQ resulted in a progressive loss of body weight over the treatment period compared to controls. It has also been found to potentially enhance the basal metabolic rate, which can contribute to increased calorie burning and, consequently, support weight loss efforts [R].
5-Amino-1MQ and Bodybuilding
5-Amino-1MQ has shown potential in enhancing muscle mass by boosting the activity of satellite cells. It also activates muscle stem cells, which may contribute to muscle growth and regeneration. It has also been suggested that 5-Amino-1MQ can help reverse the decline in aged muscle regeneration.
In addition to its muscle growth benefits, 5-Amino-1MQ has been associated with weight loss and metabolic health. It has been found to increase basal metabolic rate (BMR), which can aid in fat loss. Research suggests that NNMT inhibition significantly reduces body weight and white adipose mass, improves insulin sensitivity, and normalizes glucose tolerance and fasting blood glucose levels [R].